Structure of PDB 3f2k Chain A Binding Site BS02

Receptor Information
>3f2k Chain A (length=197) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HELTENQKNRRFEVSSSLILRNHNEPFLDRIVTCDEKWILYDNRHPKKVM
VTIWWSAAGLIHYSFLNPGETITSEKYAQEIDEMNQKLQRLQLRKGPILL
HDNARPHVAQPTLQKLNELGYEVLPHPPYSPDLLPTNYHVFKHLNNFLQG
KRFHNQQDAENAFQEFVESQSTDFYATGINQLISRWQKCVDCNGSYF
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain3f2k Chain A Residue 227 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3f2k The Crystal Structure of Transposase Domain of Human Histone-lysine N-methyltransferase SETMAR.
Resolution1.85 Å
Binding residue
(original residue number in PDB)		D38 D130
Binding residue
(residue number reindexed from 1)		D35 D102
Annotation score1
Enzymatic activity
Enzyme Commision number 2.1.1.357: [histone H3]-lysine(36) N-dimethyltransferase.
3.1.-.-
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding

View graph for
Molecular Function
External links
PDB RCSB:3f2k, PDBe:3f2k, PDBj:3f2k
PDBsum3f2k
PubMed
UniProtQ53H47|SETMR_HUMAN Histone-lysine N-methyltransferase SETMAR (Gene Name=SETMAR)

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