Structure of PDB 3f2d Chain A Binding Site BS02

Receptor Information
>3f2d Chain A (length=993) Species: 1462 (Geobacillus kaustophilus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VRRLETIVEEERRVVVQGYVFDAEVSELKSGRTLLTMKITDYTNSILVKM
FSRDKEDAELMSGVKKGMWVKVRGSVQNDTFVRDLVIIANDLNEIAANER
QDTAPEGEKRVELHLHTPMSQMDAVTSVTKLIEQAKKWGHPAIAVTDHAV
VQSFPEAYSAAKKHGMKVIYGLEANIVDDPFHVTLLAQNETGLKNLFKLV
SLSHIQYFHRVPRIPRSVLVKHRDGLLVGSGCDKGELFDNVEDIARFYDF
LEVHPPDVYKPLVKDEEMIKNIIRSIVALGEKLDIPVVATGNVHYLNPED
KIYRKILIHSQGGANPLNRHELPDVYFRTTNEMLDCFSFLGPEKAKEIVV
DNTQKIASLIGDVKPIKDELYTPRIEGADEEIREMSYRRAKEIYGDPLPK
LVEERLEKELKSIIGHGFAVIYLISHKLVKKSLDDGYLVGSRGSVGSSFV
ATMTEITEVNPLPPHYVCPNCKHSEFFNDGSVGSGFDLPDKNCPRCGTKY
KKDGHDIPFETFLGFKGDKVPDIDLNFSGEYQPRAHNYTKVLFGEDNVYR
AGTIGTVADKTAYGFVKAYASDHNLELRGAEIDRLAAGCTGVKRTTGQHP
GGIIVVPDYMEIYDFTPIQYPADDTSSEWRTTHFDFHSIHDNLLKLDILG
HDDPTVIRMLQDLSGIDPKTIPTDDPDVMGIFSSTEPLGVTPEQIMCNVG
TIGIPEFGTRFVRQMLEETRPKTFSELVQISGLSHGTDVWLGNAQELIQN
GTCTLSEVIGCRDDIMVYLIYRGLEPSLAFKIMESVRKGKGLTPEFEAEM
RKHDVPEWYIDSCKKIKYMFPKAHAAAYVLMAVRIAYFKVHHPLLYYASY
FTVRAEDFDLDAMIKGSAAIRKRIEEINAKGIQATAKEKSLLTVLEVALE
MCERGFSFKNIDLYRSQATEFVIDGNSLIPPFNAIPGLGTNVAQAIVRAR
EEGEFLSKEDLQQRGKLSKTLLEYLESRGCLDSLPDHNQLSLF
Ligand information
Receptor-Ligand Complex Structure
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PDB3f2d Structure of PolC reveals unique DNA binding and fidelity determinants.
Resolution2.51 Å
Binding residue
(original residue number in PDB)		Q983 R1001 Q1049 A1073 G1101 H1102 D1103 E1157 T1160 F1162 S1185 H1186 G1187 L1192 G1332 I1333 S1419 T1421
Binding residue
(residue number reindexed from 1)		Q532 R550 Q598 A622 G650 H651 D652 E706 T709 F711 S734 H735 G736 L741 G881 I882 S968 T970
Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003824 catalytic activity
GO:0003887 DNA-directed DNA polymerase activity
GO:0008408 3'-5' exonuclease activity
Biological Process
GO:0006260 DNA replication
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:3f2d, PDBe:3f2d, PDBj:3f2d
PDBsum3f2d
PubMed19106298
UniProtQ5L0J3

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