Structure of PDB 3f2b Chain A Binding Site BS02

Receptor Information
>3f2b Chain A (length=994) Species: 1462 (Geobacillus kaustophilus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VRRLETIVEEERRVVVQGYVFDAEVSELKSGRTLLTMKITDYTNSILVKM
FSRDKEDAELMSGVKKGMWVKVRGSVQNDTFVRDLVIIANDLNEIAANER
QDTAPEGEKRVELHLHTPMSQMDAVTSVTKLIEQAKKWGHPAIAVTDHAV
VQSFPEAYSAAKKHGMKVIYGLEANIVDDPFHVTLLAQNETGLKNLFKLV
SLSHIQYFHRVPRIPRSVLVKHRDGLLVGSGCDKGELFDNVEDIARFYDF
LEVHPPDVYKPLYVKDEEMIKNIIRSIVALGEKLDIPVVATGNVHYLNPE
DKIYRKILIHSQGGANPLNRHELPDVYFRTTNEMLDCFSFLGPEKAKEIV
VDNTQKIASLIGDVKPIKDELYTPRIEGADEEIREMSYRRAKEIYGDPLP
KLVEERLEKELKSIIGHGFAVIYLISHKLVKKSLDDGYLVGSRGSVGSSF
VATMTEITEVNPLPPHYVCPNCKHSEFFNDGSVGSGFDLPDKNCPRCGTK
YKKDGHDIPFETFLGFKGDKVPDIDLNFSGEYQPRAHNYTKVLFGEDNVY
RAGTIGTVADKTAYGFVKAYASDHNLELRGAEIDRLAAGCTGVKRTTGQH
PGGIIVVPDYMEIYDFTPIQYPADDTSSEWRTTHFDFHSIHDNLLKLDIL
GHDDPTVIRMLQDLSGIDPKTIPTDDPDVMGIFSSTEPLGVTPEQIMCNV
GTIGIPEFGTRFVRQMLEETRPKTFSELVQISGLSHGTDVWLGNAQELIQ
NGTCTLSEVIGCRDDIMVYLIYRGLEPSLAFKIMESVRKGKGLTPEFEAE
MRKHDVPEWYIDSCKKIKYMFPKAHAAAYVLMAVRIAYFKVHHPLLYYAS
YFTVRAEDFDLDAMIKGSAAIRKRIEEINAKGIQATAKEKSLLTVLEVAL
EMCERGFSFKNIDLYRSQATEFVIDGNSLIPPFNAIPGLGTNVAQAIVRA
REEGEFLSKEDLQQRGKLSKTLLEYLESRGCLDSLPDHNQLSLF
Ligand information
Receptor-Ligand Complex Structure
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PDB3f2b Structure of PolC reveals unique DNA binding and fidelity determinants.
Resolution2.39 Å
Binding residue
(original residue number in PDB)		R1001 Q1049 A1073 G1101 H1102 D1103 E1157 T1160 F1162 S1185 H1186 G1187 G1332 K1420 T1421
Binding residue
(residue number reindexed from 1)		R551 Q599 A623 G651 H652 D653 E707 T710 F712 S735 H736 G737 G882 K970 T971
Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003824 catalytic activity
GO:0003887 DNA-directed DNA polymerase activity
GO:0008408 3'-5' exonuclease activity
Biological Process
GO:0006260 DNA replication
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3f2b, PDBe:3f2b, PDBj:3f2b
PDBsum3f2b
PubMed19106298
UniProtQ5L0J3

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