Structure of PDB 3eyy Chain A Binding Site BS02

Receptor Information
>3eyy Chain A (length=133) Species: 1902 (Streptomyces coelicolor) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
STDWKSDLRQRGYRLTPQRQLVLEAVDTLEHATPDDILGEVRKTASGINI
STVYRTLELLEELGLVSHAHLGHGAPTYHLADRHHHIHLVCRDCTNVIEA
DLSVAADFTAKLREQFGFDTDMKHFAIFGRCES
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain3eyy Chain A Residue 147 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB3eyy Structural basis for the specialization of Nur, a nickel-specific Fur homolog, in metal sensing and DNA recognition
Resolution2.4 Å
Binding residue
(original residue number in PDB)		H33 H86 H88 H90
Binding residue
(residue number reindexed from 1)		H31 H84 H86 H88
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0045892 negative regulation of DNA-templated transcription
GO:1900376 regulation of secondary metabolite biosynthetic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:3eyy, PDBe:3eyy, PDBj:3eyy
PDBsum3eyy
PubMed19336416
UniProtQ9K4F8

[Back to BioLiP]