Structure of PDB 3ewa Chain A Binding Site BS02

Receptor Information
>3ewa Chain A (length=314) Species: 39152 (Methanococcus maripaludis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ADVLTELPGVGPSTADKLIEGGYLDFMKIATATIGELTDIEGISEKAAAK
MIMAARDLCDLGFKSGVELLKQRQSVWRLSTGSTELDTVLAGGIESQSVT
EFAGMFGSGKTQIMHQTCVNLQMREKIFADLEGVVEEELEAPKAVYIDTE
GTFRPERVVQMAEGAGIDGQTVLDNTFVARAYNSDMQMLFAEKIEDLIKG
GNNIKLVIIDSLTSTFRNEFTGRGKLAERQQKLGRHMATLNKLADLYNCI
VLVTNQVAAKAEQAIGGHVVGHAATFRFFLRKSKGDKRVAKLYDSPHLPD
SEAVFRITEKGIQD
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain3ewa Chain A Residue 502 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3ewa Conservation of a conformational switch in RadA recombinase from Methanococcus maripaludis.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		Q98 D246
Binding residue
(residue number reindexed from 1)		Q97 D245
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003677 DNA binding
GO:0003684 damaged DNA binding
GO:0005524 ATP binding
GO:0008094 ATP-dependent activity, acting on DNA
GO:0016887 ATP hydrolysis activity
GO:0140664 ATP-dependent DNA damage sensor activity
Biological Process
GO:0006259 DNA metabolic process
GO:0006281 DNA repair
GO:0006310 DNA recombination
GO:0006974 DNA damage response

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Molecular Function
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Biological Process
External links
PDB RCSB:3ewa, PDBe:3ewa, PDBj:3ewa
PDBsum3ewa
PubMed19465774
UniProtP0CW58|RADA_METMI DNA repair and recombination protein RadA (Gene Name=radA)

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