Structure of PDB 3etl Chain A Binding Site BS02

Receptor Information

>3etl Chain A (length=302) Species: 39152 (Methanococcus maripaludis)

ADVLTELPGVGPSTADKLIEGGYLDFMKIATATIGELTDIEGISEKAAAK
MIMAARDLCDLGFKSGVELLKQRQSVWRLSTGSTELDTVLAGGIESQSVT
EFAGMFGSGKTQIMHQTCVNLQMREKIFADLEGVVEEELEAPKAVYIDTE
GTFRPERVVQMAEGAGIDGQTVLDNTFVARAYNSDMQMLFAEKIEDLIKG
GNNIKLVIIDSLTSTFRNEFTGRGKLAERQQKLGRHMATLNKLADLYNCI
VLVTNQVAGHAATFRFFLRKSKGDKRVAKLYDSPHLPDSEAVFRITEKGI
QD

Ligand information

• Ligand ID: MG
• InChI: InChI=1S/Mg/q+2
• InChIKey: JLVVSXFLKOJNIY-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mg+2]
  CACTVS 3.341: [Mg++]
• Formula: Mg
• Name: MAGNESIUM ION
• DrugBank: DB01378
• PDB chain: 3etl Chain A Residue 502

Receptor-Ligand Complex Structure

Structure summary

• PDB: 3etl Conservation of a conformational switch in RadA recombinase from Methanococcus maripaludis.
• Resolution: 2.4 Å
• Binding residue (original residue number in PDB): Q98 D246
• Binding residue (residue number reindexed from 1): Q97 D245
• Annotation score: 1

Gene Ontology

Molecular Function

• GO:0000166 nucleotide binding
• GO:0003677 DNA binding
• GO:0003684 damaged DNA binding
• GO:0005524 ATP binding
• GO:0008094 ATP-dependent activity, acting on DNA
• GO:0016887 ATP hydrolysis activity
• GO:0140664 ATP-dependent DNA damage sensor activity

Biological Process

• GO:0006259 DNA metabolic process
• GO:0006281 DNA repair
• GO:0006310 DNA recombination
• GO:0006974 DNA damage response

External links

• PDB: RCSB:3etl, PDBe:3etl, PDBj:3etl
• PDBsum: 3etl
• PubMed: 19465774
• UniProt: P0CW58|RADA_METMI DNA repair and recombination protein RadA (Gene Name=radA)