Structure of PDB 3elv Chain A Binding Site BS02

Receptor Information
>3elv Chain A (length=145) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KHVEPQDAISPDNYMDMLGLEARDRTMYELVIYRKNDKDKGPWKRYDLNG
RSCYLVGRELGHTEIVVADIGIPEETSSKQHCVIQFRNVRGILKCYVMDL
DSSNGTCLNNVVIPGARYIELRSGDVLTLSEFEEDNDYELIFMNV
Ligand information
Ligand IDSO4
InChIInChI=1S/H2O4S/c1-5(2,3)4/h(H2,1,2,3,4)/p-2
InChIKeyQAOWNCQODCNURD-UHFFFAOYSA-L
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0[O-]S(=O)(=O)[O-]
CACTVS 3.341[O-][S]([O-])(=O)=O
ACDLabs 10.04[O-]S([O-])(=O)=O
FormulaO4 S
NameSULFATE ION
ChEMBL
DrugBankDB14546
ZINC
PDB chain3elv Chain A Residue 206 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3elv Crystal structure of the Pml1p subunit of the yeast precursor mRNA retention and splicing complex.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		E179 R181
Binding residue
(residue number reindexed from 1)		E120 R122
Annotation score3
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0003729 mRNA binding
GO:0005515 protein binding
Biological Process
GO:0000398 mRNA splicing, via spliceosome
GO:0006397 mRNA processing
GO:0006406 mRNA export from nucleus
GO:0008380 RNA splicing
GO:0051237 maintenance of RNA location
GO:1903241 U2-type prespliceosome assembly
Cellular Component
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0005686 U2 snRNP
GO:0005737 cytoplasm
GO:0070274 RES complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3elv, PDBe:3elv, PDBj:3elv
PDBsum3elv
PubMed19010333
UniProtQ07930|PML1_YEAST Pre-mRNA leakage protein 1 (Gene Name=PML1)

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