Structure of PDB 3e43 Chain A Binding Site BS02

Receptor Information
>3e43 Chain A (length=248) Species: 727 (Haemophilus influenzae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SFIKPIYQDINSILIGQKVKRPAAGEPFEKLVYKFLKENLSDLTFKQYEY
LNDLFMKNPAIIGHEARYKLFNSPTLLFLLSRGKAATENWSIENLFEEKQ
NDTADILLVKDQFYELLDVKTRNISKSAFAPNIISAYKLAQTCAKMIDNK
EFDLFDINYLEVDWELNGEDLVCVSTSFAELFKSEPSELYINWAAAMQIQ
FHVRDLDQGFNGTREEWAKSYLKHFVTQAEQRAISMIDKFVKPFKKYI
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB3e43 DNA distortion and specificity in a sequence-specific endonuclease.
Resolution2.73 Å
Binding residue
(original residue number in PDB)		A32 A33 Q109 N110 D127 K129 T130 A137 F138 P140 N141 S144 K147 A205 Q207
Binding residue
(residue number reindexed from 1)		A23 A24 Q100 N101 D118 K120 T121 A128 F129 P131 N132 S135 K138 A196 Q198
Enzymatic activity
Enzyme Commision number 3.1.21.4: type II site-specific deoxyribonuclease.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004519 endonuclease activity
GO:0009036 type II site-specific deoxyribonuclease activity
Biological Process
GO:0009307 DNA restriction-modification system

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:3e43, PDBe:3e43, PDBj:3e43
PDBsum3e43
PubMed18762194
UniProtP17743|T2C2_HAEIF Type II restriction enzyme HincII (Gene Name=hincIIR)

[Back to BioLiP]