Structure of PDB 3e40 Chain A Binding Site BS02

Receptor Information
>3e40 Chain A (length=247) Species: 727 (Haemophilus influenzae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SFIKPIYQDINSILIGQKVKRAGEPFEKLVYKFLKENLSDLTFKQYEYLN
DLFMKNPAIIGHEARYKLFNSPTLLFLLSRGKAATENWSIENLFEEKQND
TADILLVKDQFYELLDVKTRNISKSAFAPNIISAYKLAQTCAKMIDNKEF
DLFDINYLEVDWELNGEDLVCVSTSFAELFKSEPSELYINWAAAMQIQFH
VRDLDQGFNGTREEWAKSYLKHFVTQAEQRAISMIDKFVKPFKKYIL
Ligand information
Receptor-Ligand Complex Structure
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PDB3e40 DNA distortion and specificity in a sequence-specific endonuclease.
Resolution2.1 Å
Binding residue
(original residue number in PDB)		Q109 N110 D111 K129 T130 R131 S136 A137 F138 A139 P140 N141 S144 K147 A205 Q207
Binding residue
(residue number reindexed from 1)		Q98 N99 D100 K118 T119 R120 S125 A126 F127 A128 P129 N130 S133 K136 A194 Q196
Enzymatic activity
Enzyme Commision number 3.1.21.4: type II site-specific deoxyribonuclease.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004519 endonuclease activity
GO:0009036 type II site-specific deoxyribonuclease activity
Biological Process
GO:0009307 DNA restriction-modification system

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Molecular Function
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Biological Process
External links
PDB RCSB:3e40, PDBe:3e40, PDBj:3e40
PDBsum3e40
PubMed18762194
UniProtP17743|T2C2_HAEIF Type II restriction enzyme HincII (Gene Name=hincIIR)

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