Structure of PDB 3dlj Chain A Binding Site BS02

Receptor Information
>3dlj Chain A (length=471) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PPPALLEKVFQYIDLHQDEFVQTLKEWVAIESDSVQPVPRFRQELFRMMA
VAADTLQRLGARVASVDMGPQQLGQSLPIPPVILAELGSDPTKGTVCFYG
HLDVQPADRGDGWLTDPYVLTEVDGKLYGRGATDNKGPVLAWINAVSAFR
ALEQDLPVNIKFIIEGMEEAGSVALEELVEKEKDRFFSGVDYIVISDNLW
ISKPAITYGTRGNSYFMVEVKCRDQDFHSGTFGGILHEPMADLVALLGSL
VDSSGHILVPGIYDEVVPLTEEEINTYKAIHLDLEEYRNSSRVEKFLFDT
KEEILMHLWRYPSLSIHGIEGAFDEPGTKTVIPGRVIGKFSIRLVPHMNV
SAVEKQVTRHLEDVFSKRNSSNKMVVSMTLGLHPWIANIDDTQYLAAKRA
IRTVFGTEPDMIRDGSTIPIAKMFQEIVHVVLIPLGAVDDGEHSQNEKIN
RWNYIEGTKLFAAFFLEMAQL
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain3dlj Chain A Residue 2002 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3dlj Crystal structure of human carnosine dipeptidase 1.
Resolution2.26 Å
Binding residue
(original residue number in PDB)		H106 D139 D202
Binding residue
(residue number reindexed from 1)		H101 D134 D197
Annotation score1
Enzymatic activity
Enzyme Commision number 3.4.13.20: beta-Ala-His dipeptidase.
Gene Ontology
Molecular Function
GO:0004180 carboxypeptidase activity
GO:0005515 protein binding
GO:0008237 metallopeptidase activity
GO:0016787 hydrolase activity
GO:0016805 dipeptidase activity
GO:0046872 metal ion binding
GO:0070573 metallodipeptidase activity
Biological Process
GO:0006508 proteolysis
GO:0051246 regulation of protein metabolic process
Cellular Component
GO:0005576 extracellular region
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3dlj, PDBe:3dlj, PDBj:3dlj
PDBsum3dlj
PubMed
UniProtQ96KN2|CNDP1_HUMAN Beta-Ala-His dipeptidase (Gene Name=CNDP1)

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