Structure of PDB 3dac Chain A Binding Site BS02

Receptor Information
>3dac Chain A (length=85) Species: 7955 (Danio rerio) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TQVHPRAPLLQILKVAGAQEEVFTVKEVMHYLGQYIMMKQLYDKQRQHIV
HCHDDPLGELLEVGSFSVKNPSPLYEMLKRNLVIL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB3dac Structure of the human Mdmx protein bound to the p53 tumor suppressor transactivation domain.
Resolution1.8 Å
Binding residue
(original residue number in PDB)
K47 M50 G54 I57 Y63 Q68 H69 V89 P92 Y96
Binding residue
(residue number reindexed from 1)
K26 M29 G33 I36 Y42 Q47 H48 V68 P71 Y75
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0043066 negative regulation of apoptotic process
GO:0051726 regulation of cell cycle
Cellular Component
GO:0005634 nucleus

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:3dac, PDBe:3dac, PDBj:3dac
PDBsum3dac
PubMed18677113
UniProtQ7ZUW7|MDM4_DANRE Protein Mdm4 (Gene Name=mdm4)

[Back to BioLiP]