Structure of PDB 3cvx Chain A Binding Site BS02

Receptor Information

>3cvx Chain A (length=502) Species: 7227 (Drosophila melanogaster)

QRSTLVHWFRKGLRLHDNPALSHIFTAANAAPGRYFVRPIFILDPGILDW
MQVGANRWRFLQQTLEDLDNQLRKLNSRLFVVRGKPAEVFPRIFKSWRVE
MLTFETDIEPYSVTRDAAVQKLAKAEGVRVETHCSHTIYNPELVIAKNLG
KAPITYQKFLGIVEQLKVPKVLGVPEKLKNMPTPPKDEVEQKDSAAYDCP
TMKQLVKRPEELGPNKFPGGETEALRRMEESLKDEIWVARFEKPNTAPNS
LEPSTTVLSPYLKFGCLSARLFNQKLKEIIKRQPKHSQPPVSLIGQLMWR
EFYYTVAAAEPNFDRMLGNVYCMQIPWQEHPDHLEAWTHGRTGYPFIDAI
MRQLRQEGWIHHLARMAVACFLTRGDLWISWEEGQRVFEQLLLDQDWALN
AGNWMWLSASAFFHQYFRVYSPVAFGKKTDPQGHYIRKYVPELSKYPAGC
IYEPWKASLVDQRAYGCVLGTDYPHRIVKHEVVHKENIKRMGAAYKVNRE
VR

Ligand information

>3cvx Chain D (length=15)

tacctgcaaccgctg

Receptor-Ligand Complex Structure

Structure summary

• PDB: 3cvx Structure and mechanism of a coenzyme F0 accelerated (6-4) photolyase from the fruit fly
• Resolution: 3.2 Å
• Binding residue (original residue number in PDB): I157 K161 H417 Q418 Y419 F420 Y498 R502 R505
• Binding residue (residue number reindexed from 1): I154 K158 H414 Q415 Y416 F417 Y495 R499 R502

Enzymatic activity

• Catalytic site (original residue number in PDB): Q299 W302 W330 H365 W384 W407
• Catalytic site (residue number reindexed from 1): Q296 W299 W327 H362 W381 W404

Gene Ontology

Molecular Function

• GO:0000166 nucleotide binding
• GO:0003677 DNA binding
• GO:0003904 deoxyribodipyrimidine photo-lyase activity
• GO:0071949 FAD binding

Biological Process

• GO:0032922 circadian regulation of gene expression
• GO:0043153 entrainment of circadian clock by photoperiod

Cellular Component

• GO:0005634 nucleus
• GO:0005737 cytoplasm

External links

• PDB: RCSB:3cvx, PDBe:3cvx, PDBj:3cvx
• PDBsum: 3cvx
• UniProt: Q8SXK5