Structure of PDB 3cjq Chain A Binding Site BS02

Receptor Information
>3cjq Chain A (length=253) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MWVYRLKGTLEALDPILPGLFDGGARGLWEREGEVWAFFPAPVDLPYEGV
WEEVGDDWLEAWRRDLKPALAPPFVVLAPWHTWEGAEIPLVIEPGMAFGT
GHHETTRLALKALARHLRPGDKVLDLGTGSGVLAIAAEKLGGKALGVDID
PMVLPQAEANAKRNGVRPRFLEGSLEAALPFGPFDLLVANLYAELHAALA
PRYREALVPGGRALLTGILKDRAPLVREAMAGAGFRPLEEAAEGEWVLLA
YGR
Ligand information
Ligand ID2MM
InChIInChI=1S/C7H15NO2S/c1-8(2)6(7(9)10)4-5-11-3/h6H,4-5H2,1-3H3,(H,9,10)/t6-/m0/s1
InChIKeyFLEXUHXAXRFRAU-LURJTMIESA-N
SMILES
SoftwareSMILES
CACTVS 3.341CSCC[C@H](N(C)C)C(O)=O
CACTVS 3.341CSCC[CH](N(C)C)C(O)=O
OpenEye OEToolkits 1.5.0CN(C)[C@@H](CCSC)C(=O)O
ACDLabs 10.04O=C(O)C(N(C)C)CCSC
OpenEye OEToolkits 1.5.0CN(C)C(CCSC)C(=O)O
FormulaC7 H15 N O2 S
NameN,N-dimethyl-L-methionine
ChEMBLCHEMBL1229963
DrugBank
ZINCZINC000001677421
PDB chain3cjq Chain B Residue 1 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3cjq Multiple-Site Trimethylation of Ribosomal Protein L11 by the PrmA Methyltransferase.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		N191 L192 G218
Binding residue
(residue number reindexed from 1)		N190 L191 G217
Annotation score1
Enzymatic activity
Enzyme Commision number 2.1.1.-
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0008168 methyltransferase activity
GO:0008276 protein methyltransferase activity
GO:0042054 histone methyltransferase activity
Biological Process
GO:0006338 chromatin remodeling
GO:0006479 protein methylation
GO:0032259 methylation
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3cjq, PDBe:3cjq, PDBj:3cjq
PDBsum3cjq
PubMed18611379
UniProtQ84BQ9|PRMA_THET8 Ribosomal protein L11 methyltransferase (Gene Name=prmA)

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