Structure of PDB 3c94 Chain A Binding Site BS02

Receptor Information
>3c94 Chain A (length=458) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QQSTFLFHDYETFGTHPALDRPAQFAAIRTDSEFNVIGEPEVFYCKPADD
YLPQPGAVLITGITPQEARAKGENEAAFAARIHSLFTVPKTCILGYNNVR
FDDEVTRNIFYRNFYDPYAWSWQHDNSRWDLLDVMRACYALRPEGINWPE
NDDGLPSFRLEHLTKANGIEHSDAMADVYATIAMAKLVKTRQPRLFDYLF
THRNKHKLMALIDVPQMKPLVHVSGMFGAWRGNTSWVAPLAWHPENRNAV
IMVDLAGDISPLLELDSDTLRERLYTAKTDLNAAVPVKLVHINKCPVLAQ
ANTLRPEDADRLGINRQHCLDNLKILRENPQVREKVVAIFASDNVDAQLY
NGFFSDADRAAMKIVLETEPRNLPALDITFVDKRIEKLLFNYRARNFPGT
LDYAEQQRWLEHRRQVFTPEFLQGYADELQMLVQQYADDKEKVALLKALW
QYADEIVE
Ligand information
>3c94 Chain C (length=3) Species: 1125630 (Klebsiella pneumoniae subsp. pneumoniae HS11286) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
IPF
Receptor-Ligand Complex Structure
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PDB3c94 Structural basis of Escherichia coli single-stranded DNA-binding protein stimulation of exonuclease I.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		P228 W245 A312 R327 L331
Binding residue
(residue number reindexed from 1)		P219 W236 A301 R316 L320
Enzymatic activity
Enzyme Commision number 3.1.11.1: exodeoxyribonuclease I.
Gene Ontology
Molecular Function
GO:0000175 3'-5'-RNA exonuclease activity
GO:0000287 magnesium ion binding
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003697 single-stranded DNA binding
GO:0004527 exonuclease activity
GO:0004529 DNA exonuclease activity
GO:0005515 protein binding
GO:0008310 single-stranded DNA 3'-5' DNA exonuclease activity
GO:0046872 metal ion binding
GO:0051575 5'-deoxyribose-5-phosphate lyase activity
Biological Process
GO:0006259 DNA metabolic process
GO:0006274 DNA replication termination
GO:0006281 DNA repair
GO:0006308 DNA catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3c94, PDBe:3c94, PDBj:3c94
PDBsum3c94
PubMed18591666
UniProtP04995|EX1_ECOLI Exodeoxyribonuclease I (Gene Name=sbcB)

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