Structure of PDB 3c25 Chain A Binding Site BS02

Receptor Information
>3c25 Chain A (length=354) Species: 1823 (Nocardia otitidiscaviarum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ANFIAEFFGHRVYPEVVSTEAARNDQATGTCPFLTAAKLVETSCVKAETS
RGVCVVNTAVDNERYDWLVCPNRALDPLFMSAASRKLFGYGPTEPLQFIA
APTLADQAVRDGIREWLDRGVHVVAYFQEKLGGELSISKTDSSPEFSFDW
TLAEVESIYPVPKIKRYGVLEIQTMDFHGSYKHAVGAIDIALVEGIDFHG
WLPTPAGRAALSKKMEGPNLSNVFKRTFYQMAYKFALSGHQRCAGTGFAI
PQSVWKSWLRHLANPTLIDNGDGTFSLGDTRNDSENAWIFVFELDPDTDA
SPRPLAPHLEIRVNVDTLIDLALRESPRAALGPSGPVATFTDKVEARMLR
FWPK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3c25 Structures of the Rare-Cutting Restriction Endonuclease NotI Reveal a Unique Metal Binding Fold Involved in DNA Binding.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		K57 T60 S61 V80 E156 F157 S158 D160 Q184 T185 M186 D187 F188 G190 S191 Y192 R237 Q241 K245 R358
Binding residue
(residue number reindexed from 1)		K46 T49 S50 V69 E145 F146 S147 D149 Q173 T174 M175 D176 F177 G179 S180 Y181 R226 Q230 K234 R347
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0042802 identical protein binding
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:3c25, PDBe:3c25, PDBj:3c25
PDBsum3c25
PubMed18400177
UniProtQ2I6W2

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