Structure of PDB 3buc Chain A Binding Site BS02

Receptor Information
>3buc Chain A (length=200) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SWRHIRAEGLDSSYTVLFGKAEADEIFQELEKEVEYFTGALARVQVFGKW
HSVPRKQATYGDAGLTYTFSGLTLSPKPWIPVLERIRDHVSGVTGQTFNF
VLINRYKDGSDHICEHRDDERELAPGSPIASVSFGASRDFVFRHKDSRPS
RRVAVVRLPLAHGSLLMMNHPTNTHWYHSLPVRKKVLAPRVNLTFRKILL
Ligand information
Receptor-Ligand Complex Structure
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PDB3buc Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA.
Resolution2.59 Å
Binding residue
(original residue number in PDB)
F102 G103 K104 W105 R198 R241 K242
Binding residue
(residue number reindexed from 1)
F47 G48 K49 W50 R143 R183 K184
Enzymatic activity
Enzyme Commision number 1.14.11.33: DNA oxidative demethylase.
Gene Ontology

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Biological Process
External links
PDB RCSB:3buc, PDBe:3buc, PDBj:3buc
PDBsum3buc
PubMed18432238
UniProtQ6NS38|ALKB2_HUMAN DNA oxidative demethylase ALKBH2 (Gene Name=ALKBH2)

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