Structure of PDB 3bso Chain A Binding Site BS02

Receptor Information
>3bso Chain A (length=479) Species: 11983 (Norwalk virus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KGTYCGAPILGPGSAPKLSTKTKFWRSSTAPLPPGTYEPAYLGGKDPRVK
GGPSLQQVMRDQLKPFTEPRGKPPKPSVLEAAKKTIINVLEQTIDPPDKW
SFAQACASLDKTTSSGHPHHMRKNDCWNGESFTGKLADQASKANLMFEEG
KNMTPVYTGALKDELVKTDKIYGKIKKRLLWGSDLATMIRCARAFGGLMD
ELKTHCVTLPIRVGMNMNEDGPIIFERHSRYRYHYDADYSRWDSTQQRAV
LAAALEIMVKFSSEPHLAQVVAEDLLSPSVVDVGDFTISINEGLPSGVPC
TSQWNSIAHWLLTLCALSEVTNLSPDIIQANSLFSFYGDDEIVSTDIKLD
PEKLTAKLKEYGLKPTRPDKTEGPLVISEDLNGLTFLRRTVTRDPAGWFG
KLEQSSILRQMYWTRGPNHEDPSETMIPHSQRPIQLMSLLGEAALHGPAF
YSKISKLVIAELDFYVPRQEPMFRWMRFS
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3bso Structural insights into mechanisms of catalysis and inhibition in norwalk virus polymerase.
Resolution1.74 Å
Binding residue
(original residue number in PDB)		T117 S118 K127 A164 K166 L184 G186 M192 K207 G218 M219 N220 G301 P303 Y341 N422
Binding residue
(residue number reindexed from 1)		T113 S114 K123 A160 K162 L180 G182 M188 K203 G214 M215 N216 G297 P299 Y337 N418
Enzymatic activity
Enzyme Commision number 3.4.22.66: calicivirin.
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003968 RNA-dependent RNA polymerase activity
GO:0004386 helicase activity
GO:0005524 ATP binding
Biological Process
GO:0006351 DNA-templated transcription
GO:0039694 viral RNA genome replication

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Molecular Function
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Biological Process
External links
PDB RCSB:3bso, PDBe:3bso, PDBj:3bso
PDBsum3bso
PubMed18184655
UniProtQ70ET3

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