Structure of PDB 3awo Chain A Binding Site BS02

Receptor Information
>3awo Chain A (length=368) Species: 9031 (Gallus gallus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MWLGALLDTLPTPALTIDRTTARRNAERMRERCRALGVRLRPHVKTHKTL
EGGLLATGGTRRGIAVSTLAEARFFADGGFDDILLAYPVPTARLEECAGL
ARRLDAFHVLLDRPEALASLRQRPLGHGKRWLVWLKLDCGRAGVRPTDPA
ALELAQAIANDAPEEVTLVGVYAHCGNTYGCSGADTIQAIARTTTNAVLS
FVAALRQAGVPCPQASIGSTPSCSHPIPEMSQLTELHPGNYIFYDLQQTQ
LGSCQPQDVAIRVLTRVIGHYAHRGQLLVDCGWAALSLHGAGGPQGCAAI
DGHPELRLVGLTQEHGLLEHQMDFGRFPVGSVLALIPYHACATAAMHPVY
YVHEEGKVVALWHPVRGW
Ligand information
Ligand IDDSN
InChIInChI=1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m1/s1
InChIKeyMTCFGRXMJLQNBG-UWTATZPHSA-N
SMILES
SoftwareSMILES
CACTVS 3.341N[CH](CO)C(O)=O
OpenEye OEToolkits 1.5.0C([C@H](C(=O)O)N)O
CACTVS 3.341N[C@H](CO)C(O)=O
OpenEye OEToolkits 1.5.0C(C(C(=O)O)N)O
ACDLabs 10.04O=C(O)C(N)CO
FormulaC3 H7 N O3
NameD-SERINE
ChEMBLCHEMBL285123
DrugBankDB03929
ZINCZINC000000895342
PDB chain3awo Chain A Residue 402 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3awo Crystal structure of a zinc-dependent D-serine dehydratase from chicken kidney.
Resolution2.65 Å
Binding residue
(original residue number in PDB)		K45 H176
Binding residue
(residue number reindexed from 1)		K45 H174
Annotation score5
Enzymatic activity
Enzyme Commision number 4.3.1.18: D-serine ammonia-lyase.
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0008721 D-serine ammonia-lyase activity
GO:0016829 lyase activity
GO:0030170 pyridoxal phosphate binding
GO:0046872 metal ion binding
Biological Process
GO:0036088 D-serine catabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0030425 dendrite
GO:0042995 cell projection

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3awo, PDBe:3awo, PDBj:3awo
PDBsum3awo
PubMed21676877
UniProtA0A8V1ABE9|DSD1_CHICK D-serine dehydratase (Gene Name=DSD)

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