Structure of PDB 3ap1 Chain A Binding Site BS02

Receptor Information
>3ap1 Chain A (length=298) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LVMVVEYRYGKAMPLIFVGGVPRSGTTLMRAMLDAHPEVRCGEETRIIPR
VLAMRQAWSKSGREKLRLDEAGVTDEVLDAAMQAFILEVIAKHGEPARVL
CNKDPFTLKSSVYLSRLFPNSKFLLMVRDGRASVHSMITRKVTIAGFDLS
SYRDCLTKWNKAIEVMYAQCMEVGKEKCLPVYYEQLVLHPRRSLKLILDF
LGIAWSDAVLHHEDLIGKPGGVSLSKIERSTDQVIKPVNLEALSKWTGHI
PGDVVRDMAQIAPMLAQLGYDPYANPPNYGNPDPFVINNTQRVLKGDY
Ligand information
Receptor-Ligand Complex Structure
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PDB3ap1 Crystal structure of human tyrosylprotein sulfotransferase-2 reveals the mechanism of protein tyrosine sulfation reaction.
Resolution1.9 Å
Binding residue
(original residue number in PDB)		W113 S116 R118 E119 R122
Binding residue
(residue number reindexed from 1)		W58 S61 R63 E64 R67
Enzymatic activity
Enzyme Commision number 2.8.2.20: protein-tyrosine sulfotransferase.
Gene Ontology
Molecular Function
GO:0008476 protein-tyrosine sulfotransferase activity
Biological Process
GO:0006478 peptidyl-tyrosine sulfation

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Molecular Function
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Biological Process
External links
PDB RCSB:3ap1, PDBe:3ap1, PDBj:3ap1
PDBsum3ap1
PubMed23481380
UniProtO60704|TPST2_HUMAN Protein-tyrosine sulfotransferase 2 (Gene Name=TPST2)

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