Structure of PDB 3a2k Chain A Binding Site BS02

Receptor Information
>3a2k Chain A (length=462) Species: 1462 (Geobacillus kaustophilus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MIDKVRAFIHRHQLLSEGAAVIVGVSGGPDSLALLHVFLSLRDEWKLQVI
AAHVDHMFRGRESEEEMEFVKRFCVERRILCETAQIDVPAFQRSAGLGAQ
EAARICRYRFFAELMEKHQAGYVAVGHHGDDQVETILMRLVRGSTSKGYA
GIPVKRPFHGGYLIRPFLAVSRAEIEAYCRQMGLSPRCDPSNEKDDYTRN
RFRHHIVPLLRQENPRLHERFQQYSEMMAEDEQFLEELAADALNKVMEKQ
HRDAALSIGPFLELPRPLQRRVLQLLLLRLYGGVPPTLTSVHIGHILMLC
ERGRPSGMIDLPKGLKVIRSYDRCLFTFDAESGEKGYWFELPVPALLPLP
NGYAIISEFGEHYPRKQAGNDWFVVDPASVSLPLRVRTRRRGDRMVLKGT
GGTKKLKEIFIEAKIPRMERDRWPIVEDADGRILWVPGLKKSAFEAQNRG
QARYILLQYQAM
Ligand information
>3a2k Chain D (length=77) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggaccuuuagcucaguugguuagagcagacggcucauaaccguccggccg
uagguucgaguccuacaagguccacca
<<<<<<<..<<<<.........>>>>.<<<<<.......>>>>>.....<
<<<<.......>>>>>>>>>>>>....
Receptor-Ligand Complex Structure
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PDB3a2k Structural basis for translational fidelity ensured by transfer RNA lysidine synthetase.
Resolution3.65 Å
Binding residue
(original residue number in PDB)		N214 R216
Binding residue
(residue number reindexed from 1)		N214 R216
Enzymatic activity
Enzyme Commision number 6.3.4.19: tRNA(Ile)-lysidine synthetase.
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0005524 ATP binding
GO:0016874 ligase activity
GO:0016879 ligase activity, forming carbon-nitrogen bonds
GO:0032267 tRNA(Ile)-lysidine synthase activity
Biological Process
GO:0006400 tRNA modification
GO:0008033 tRNA processing
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3a2k, PDBe:3a2k, PDBj:3a2k
PDBsum3a2k
PubMed19847269
UniProtQ5L3T3|TILS_GEOKA tRNA(Ile)-lysidine synthase (Gene Name=tilS)

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