Structure of PDB 2zzn Chain A Binding Site BS02

Receptor Information
>2zzn Chain A (length=336) Species: 2190 (Methanocaldococcus jannaschii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MPLCLKINKKHGEQTRRILIENNLLNKDYKITSEGNYLYLPIKDVDEDIL
KSILNIEFELVDKELEEKKIIKKPSFREIISKKYRKEIDEGLISLSYDVV
GDLVILQISDEVDEKIRKEIGELAYKLIPCKGVFRRKSEVKGEFRVRELE
HLAGENRTLTIHKENGYRLWVDIAKVYFSPRLGGERARIMKKVSLNDVVV
DMFAGVGPFSIACKNAKKIYAIDINPHAIELLKKNIKLNKLEHKIIPILS
DVREVDVKGNRVIMNLPKFAHKFIDKALDIVEEGGVIHYYTIGKDFDKAI
KLFEKKCDCEVLEKRIVKSYAPREYILALDFKINKK
Ligand information
>2zzn Chain D (length=71) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gccgggguagucuaggggcuaggcagcggacugcagauccgccuuacgug
gguucaaaucccacccccggc
<<<<<<<..<<<<.......>>>>.<<<<<.......>>>>>.....<<<
<<.......>>>>>>>>>>>>
Receptor-Ligand Complex Structure
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PDB2zzn Tertiary structure checkpoint at anticodon loop modification in tRNA functional maturation.
Resolution2.95 Å
Binding residue
(original residue number in PDB)		K191 V193 L195
Binding residue
(residue number reindexed from 1)		K191 V193 L195
Enzymatic activity
Enzyme Commision number 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity
GO:0008175 tRNA methyltransferase activity
GO:0016740 transferase activity
GO:0052906 tRNA (guanine(37)-N1)-methyltransferase activity
Biological Process
GO:0002939 tRNA N1-guanine methylation
GO:0008033 tRNA processing
GO:0030488 tRNA methylation
GO:0032259 methylation
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2zzn, PDBe:2zzn, PDBj:2zzn
PDBsum2zzn
PubMed19749755
UniProtQ58293|TRM5B_METJA tRNA (guanine(37)-N1)-methyltransferase Trm5b (Gene Name=trm5b)

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