Structure of PDB 2zoo Chain A Binding Site BS02

Receptor Information

>2zoo Chain A (length=438) Species: 326442 (Pseudoalteromonas translucida TAC125)

LKTEQAILTPPPMVPPAINRDHSAKVVINLETREQVGRIADGVEYVFWSF
GETVPGSFIRVREGDEIEFNLSNHPSSKMPHNIDLHAVTGPGGGAESSFT
APGHTSTFNFKALNPGLYIYHCATAPVGMHIANGMYGLILVEPKEGLAPV
DREYYLVQGDFYTKGEFGEAGLQPFDMAKAIDEDADYVVFNGSVGSTTDE
NSLTAKVGETVRLYIGNGGPNLVSSFHVIGEIFDTVYVEGGSLKNHNVQT
TLIPAGGAAIVEFKVEVPGTFILVDHSIFRAFNKGALAMLKVEGPDDHSI
FTGKTAENVYLPEGSAIQSLDNTFTKITANNKDEQIRFGQRVYEANCMAC
HQANGEGIPGAFPPLAKSDYLNNNPLLGVNAIIKGLSGPIKVNNVNYNGV
MPAMNLNDEDIANVITFVLNNWDNAGGKVSAEQVAKQR

Ligand information

• Ligand ID: CU
• InChI: InChI=1S/Cu/q+2
• InChIKey: JPVYNHNXODAKFH-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Cu+2]
  CACTVS 3.341: [Cu++]
• Formula: Cu
• Name: COPPER (II) ION
• DrugBank: DB14552
• PDB chain: 2zoo Chain A Residue 501

Receptor-Ligand Complex Structure

Structure summary

• PDB: 2zoo Electron transfer processes within and between proteins containing the HEME C and blue Cu
• Resolution: 1.95 Å
• Binding residue (original residue number in PDB): H89 H124
• Binding residue (residue number reindexed from 1): H86 H121
• Annotation score: 1

Enzymatic activity

• Catalytic site (original residue number in PDB): H84 D87 H89 H124 C125 H133 M138 H230 Q252 T253 H279
• Catalytic site (residue number reindexed from 1): H81 D84 H86 H121 C122 H130 M135 H227 Q249 T250 H276
• Enzyme Commision number: 1.7.2.1: nitrite reductase (NO-forming).

Gene Ontology

Molecular Function

• GO:0005507 copper ion binding
• GO:0009055 electron transfer activity
• GO:0016491 oxidoreductase activity
• GO:0020037 heme binding
• GO:0046872 metal ion binding
• GO:0050421 nitrite reductase (NO-forming) activity

Biological Process

• GO:0019333 denitrification pathway
• GO:0042128 nitrate assimilation

Cellular Component

• GO:0042597 periplasmic space

External links

• PDB: RCSB:2zoo, PDBe:2zoo, PDBj:2zoo
• PDBsum: 2zoo
• UniProt: Q3IGF7