Structure of PDB 2zkf Chain A Binding Site BS02
Receptor Information
>2zkf Chain A (length=209) Species:
10090
(Mus musculus) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
GMACVGRTTECTIVPANHFGPIPGVPVGTMWRFRVQVSESGVHRPHVAGI
HGRSNDGAYSLVLAGGYEDDVDNGNYFTYTGSGGRDLSGNKRTAGQSSDQ
KLTNNNRALALNCHSPINEKGAEAEDWRQGKPVRVVRNMKGGKHSKYAPA
EGNRYDGIYKVVKYWPERGKSGFLVWRYLLRRDDTEPEPWTREGKDRTRQ
LGLTMQYPE
Ligand information
>2zkf Chain D (length=11) [
Search DNA sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
ctatccggtga
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
2zkf
Recognition of hemi-methylated DNA by the SRA protein UHRF1 by a base-flipping mechanism
Resolution
2.55 Å
Binding residue
(original residue number in PDB)
G405 M406 A407 F437 R438 V451 A452 G453 A468 G469 G470 Y471 D474 Y483 T484 G487 R496
Binding residue
(residue number reindexed from 1)
G1 M2 A3 F33 R34 V47 A48 G49 A64 G65 G66 Y67 D70 Y79 T80 G83 R92
Enzymatic activity
Enzyme Commision number
2.3.2.27
: RING-type E3 ubiquitin transferase.
External links
PDB
RCSB:2zkf
,
PDBe:2zkf
,
PDBj:2zkf
PDBsum
2zkf
PubMed
18772891
UniProt
Q8VDF2
|UHRF1_MOUSE E3 ubiquitin-protein ligase UHRF1 (Gene Name=Uhrf1)
[
Back to BioLiP
]
