Structure of PDB 2zfe Chain A Binding Site BS02

Receptor Information

>2zfe Chain A (length=227) Species: 64091 (Halobacterium salinarum NRC-1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

TGRPEWIWLALGTALMGLGTLYFLVKGMGVSDPDAKKFYAITTLVPAIAF
TMYLSMLLGYGLTMVPFGGEQNPIYWARYADWLFTTPLLLLDLALLVDAD
QGTILALVGADGIMIGTGLVGALTKVYSYRFVWWAISTAAMLYILYVLFF
GFTSKAESMRPEVASTFKVLRNVTVVLWSAYPVVWLIGSEGAGIVPLNIE
TLLFMVLDVSAKVGFGLILLRSRAIFG

Ligand information

Ligand ID

InChI

InChI=1S/Xe

InChIKey

FHNFHKCVQCLJFQ-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 CACTVS 3.341 OpenEye OEToolkits 1.5.0	[Xe]

Formula

Name

XENON

PDB chain

2zfe Chain A Residue 638 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	2zfe Effect of xenon binding to a hydrophobic cavity on the proton pumping cycle in bacteriorhodopsin
Resolution	2.5 Å
Binding residue (original residue number in PDB)	L94 L95 I108
Binding residue (residue number reindexed from 1)	L90 L91 I104
Annotation score	1

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0005216	monoatomic ion channel activity
GO:0009881	photoreceptor activity
GO:0015454	light-driven active monoatomic ion transmembrane transporter activity

	Biological Process
GO:0006811	monoatomic ion transport
GO:0007602	phototransduction
GO:1902600	proton transmembrane transport

	Cellular Component
GO:0005886	plasma membrane
GO:0016020	membrane

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Cellular Component

External links

PDB	RCSB:2zfe, PDBe:2zfe, PDBj:2zfe
PDBsum	2zfe
PubMed	18930734
UniProt	P02945\|BACR_HALSA Bacteriorhodopsin (Gene Name=bop)

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