Structure of PDB 2z72 Chain A Binding Site BS02

Receptor Information
>2z72 Chain A (length=338) Species: 50422 (Shewanella sp.) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ATEFDGPYVITPISGQSTAYWICDNRLKTTSIEKLQVNRPEHCGDLPETK
LSSEIKQIMPDTYLGIKKVVALSDVHGQYDVLLTLLKKQKIIDSDGNWAF
GEGHMVMTGDIFDRGHQVNEVLWFMYQLDQQARDAGGMVHLLMGNHEQMV
LGGDLRYVHQRYDIATTLINRPYNKLYSADTEIGQWLRSKNTIIKINDVL
YMHGGISSEWISRELTLDKANALYRANVDASKKSLKADDLLNFLFFGNGP
TWYRGYFSETFTEAELDTILQHFNVNHIVVGHTSQERVLGLFHNKVIAVD
SSIKVGKSGELLLLENNRLIRGLYDGTRETLQENSLNQ
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain2z72 Chain A Residue 402 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2z72 The role of group bulkiness in the catalytic activity of psychrophile cold-active protein tyrosine phosphatase
Resolution1.1 Å
Binding residue
(original residue number in PDB)		D114 N149 H207 H286
Binding residue
(residue number reindexed from 1)		D110 N145 H203 H282
Annotation score1
Enzymatic activity
Enzyme Commision number 3.1.3.48: protein-tyrosine-phosphatase.
Gene Ontology
Molecular Function
GO:0004725 protein tyrosine phosphatase activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:2z72, PDBe:2z72, PDBj:2z72
PDBsum2z72
PubMed18647345
UniProtQ9S427

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