Structure of PDB 2z6q Chain A Binding Site BS02

Receptor Information

>2z6q Chain A (length=327) Species: 735 (Haemophilus parahaemolyticus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MIEIKDKQLTGLRFIDLFAGLGGFRLALESCGAECVYSNEWDKYAQEVYE
MNFGEKPEGDITQVNEKTIPDHDILCAGFPCQAFSISGKQKGFEDSRGTL
FFDIARIVREKKPKVVFMENVKNFASHDNGNTLEVVKNTMNELDYSFHAK
VLNALDYGIPQKREAIYMICFRNDLNIQNFQFPKPFELNTFVKDLLLPDS
EVEHLVIDRKDLVMTNQEIEQTTPKTVRLGIVGKGGQGERIYSTRGIAIT
LSAYGGGIFAKTGGYLVNGKTRKLHPRECARVMGYPDSYKVHPSTSQAYK
QFGNSVVINVLQYIAYNIGSSLNFKPY

Ligand information

>2z6q Chain D (length=6) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

tgatag

Receptor-Ligand Complex Structure

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Structure summary

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PDB	2z6q The role of Arg165 towards base flipping, base stabilization and catalysis in M.HhaI
Resolution	2.79 Å
Binding residue (original residue number in PDB)	I86 S87 K162 T226 R228 Q237 R240 Y242 I249 T250
Binding residue (residue number reindexed from 1)	I86 S87 K162 T226 R228 Q237 R240 Y242 I249 T250

Enzymatic activity

Enzyme Commision number

2.1.1.37: DNA (cytosine-5-)-methyltransferase.

Gene Ontology

	Molecular Function
GO:0003677	DNA binding
GO:0003886	DNA (cytosine-5-)-methyltransferase activity
GO:0008168	methyltransferase activity

	Biological Process
GO:0009307	DNA restriction-modification system
GO:0032259	methylation

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Molecular Function

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Biological Process

External links

PDB	RCSB:2z6q, PDBe:2z6q, PDBj:2z6q
PDBsum	2z6q
PubMed	16926025
UniProt	P05102\|MTH1_HAEPH Type II methyltransferase M.HhaI (Gene Name=hhaIM)

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