Structure of PDB 2ykg Chain A Binding Site BS02

Receptor Information
>2ykg Chain A (length=636) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NLYSKPRNYQLELALPAMKGKNTIICAPTGCGKTFVSLLICEHHLKKFPQ
GQKGKVVFFANQIPVYEQNKSVFSKYFERHGYRVTGISGATAENVPVEQI
VENNDIIILTPQILVNNLKKGTIPSLSIFTLMIFDECHNTSKQHPYNMIM
FNYLDQKLGGSSGPLPQVIGLTASVGVGDAKTTDEALDYICKLCASLDAS
VIATVKHNLEELEQVVYKPQKFFRKVESRISDKFKYIIAQLMRDTESLAK
RICKDLENLSQIQNREFGTQKYEQWIVTVQKACMVDEESRICKALFLYTS
HLRKYNDALIISEHARMKDALDYLKDFFSNVRAAGFDEIEQDLTQRFEEK
LQELESVSRDPSNENPKLEDLCFILQEEYHLNPETITILFVKTRALVDAL
KNWIEGNPKLSFLKPGIDHNILIATSVADEGAQCNLVILYEYVVIKMRGS
KCFLLTSNAGVIEKEQINMYKEKMMNDSILRLQTWDEAVFREKILHIQTH
EKFIRDSQEKPKPVPDKENKKLLCRKCKALACYTADVRVIEDCHYTVLGD
AFKECFVSRPHPKPKQFSSFEKRAKIFCARQNCSHDWGIHVKYKTFEIPV
IKIESFVVEDIATGVQTLYSKWKDFHFEKIPFDPAE
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2ykg Structural Insights Into RNA Recognition by Rig-I.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		N298 Q299 I300 S325 G326 T347 Q349 Q498 I499 F853 S854
Binding residue
(residue number reindexed from 1)		N61 Q62 I63 S88 G89 T110 Q112 Q261 I262 F567 S568
Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0005524 ATP binding

View graph for
Molecular Function
External links
PDB RCSB:2ykg, PDBe:2ykg, PDBj:2ykg
PDBsum2ykg
PubMed22000018
UniProtO95786|RIGI_HUMAN Antiviral innate immune response receptor RIG-I (Gene Name=RIGI)

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