Structure of PDB 2yk7 Chain A Binding Site BS02

Receptor Information
>2yk7 Chain A (length=322) Species: 491 (Neisseria meningitidis serogroup B) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PVNLIFCYTILQMKVAERIMAQHPGERFYVVLMSENNNEKYDYYFNQIKD
KAEWAYFFHLPYGLNKSFNFIPTMAELKVKAMLLPKVKRIYLASLEKVSI
AAFLSTYPDAEIKTFDDGTINLIQSSSYLGDEFSVNGTIKRNFARMMIGD
WSIAKTRNASDEHYTIFKGLKNIMDDGRRKMTYLPLFDASELKAGDETGG
TVRILLGSPDKEMKEISEKAAKNFNIQYVAPHPRQTYGLSGVTTLNSPYV
IEDYILREIKKNPHTRYEIYTFFSGAALTMKDFPNVHVYALKPASLPEDY
WLKPVYALFTQSGIPILTFDDK
Ligand information
Ligand IDEDO
InChIInChI=1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
InChIKeyLYCAIKOWRPUZTN-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341		OCCO
OpenEye OEToolkits 1.5.0C(CO)O
FormulaC2 H6 O2
Name1,2-ETHANEDIOL;
ETHYLENE GLYCOL
ChEMBLCHEMBL457299
DrugBank
ZINCZINC000005224354
PDB chain2yk7 Chain A Residue 1373 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2yk7 Structure and Mechanism of the Lipooligosaccharide Sialyltransferase from Neisseria Meningitidis
Resolution2.18 Å
Binding residue
(original residue number in PDB)		L59 V63
Binding residue
(residue number reindexed from 1)		L11 V15
Annotation score1
Enzymatic activity
Enzyme Commision number 2.4.3.6: N-acetyllactosaminide alpha-2,3-sialyltransferase.
External links
PDB RCSB:2yk7, PDBe:2yk7, PDBj:2yk7
PDBsum2yk7
PubMed21880735
UniProtP72097|LST_NEIMB N-acetyllactosaminide alpha-2,3-sialyltransferase (Gene Name=lst)

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