Structure of PDB 2yeq Chain A Binding Site BS02

Receptor Information

>2yeq Chain A (length=522) Species: 1423 (Bacillus subtilis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

APNFSSYPFTLGVASGDPLSDSVVLWTRLAPDPLNGGGMPKQAVPVKWEV
AKDEHFRKIVRKGTEMAKPSLAHSVHVEADGLEPNKVYYYRFKTGHELSP
VGKTKTLPAPGANVPQMTFAFASCQQYEHGYYTAYKHMAKEKLDLVFHLG
DYIYEYGPNEYVSKTGNVRTHNSAEIITLQDYRNRHAQYRSDANLKAAHA
AFPWVVTWDDHEVENNYANKIPEKGQSVEAFVLRRAAAYQAYYEHMPLRI
SSLPNGPDMQLYRHFTYGNLASFNVLDTRQYRDDQANNDGNKPPSDESRN
PNRTLLGKEQEQWLFNNLGSSTAHWNVLAQQIFFAKWNFGTSASPIYSMD
SWDGYPAQRERVINFIKSKNLNNVVVLTGDVHASWASNLHVDFEKTSSKI
FGAEFVGTSITSGGNGADKRADTDQILKENPHIQFFNDYRGYVRCTVTPH
QWKADYRVMPFVTEPGAAISTRASFVYQKDQTGLRKVSSTTIQGGVKQSD
EVEEDRFFSHNKAHEKQMIKKR

Ligand information

Ligand ID

InChI

InChI=1S/Ca/q+2

InChIKey

BHPQYMZQTOCNFJ-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Ca++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Ca+2]

Formula

Name

CALCIUM ION

PDB chain

2yeq Chain A Residue 1525 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	2yeq Crystal Structure of the Bacillus Subtilis Phosphodiesterase Phod Reveals an Iron and Calcium-Containing Active Site.
Resolution	1.93 Å
Binding residue (original residue number in PDB)	D151 D209 D210 D380
Binding residue (residue number reindexed from 1)	D151 D209 D210 D380
Annotation score	1

Enzymatic activity

Enzyme Commision number

3.1.3.1: alkaline phosphatase.

Gene Ontology

	Molecular Function
GO:0004035	alkaline phosphatase activity
GO:0016787	hydrolase activity

View graph for
Molecular Function

External links

PDB	RCSB:2yeq, PDBe:2yeq, PDBj:2yeq
PDBsum	2yeq
PubMed	25217636
UniProt	P42251\|PPBD_BACSU Alkaline phosphatase D (Gene Name=phoD)

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