Structure of PDB 2y8e Chain A Binding Site BS02

Receptor Information
>2y8e Chain A (length=165) Species: 7227 (Drosophila melanogaster) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDR
TVRLQLWDTAGQERFRSLIPSYIRDSTVAVVVYDITNTNSFHQTSKWIDD
VRTERGSDVIIMLVGNKTDLSDKRQVSTEEGERKAKELNVMFIETSAKAG
YNVKQLFRRVAAALP
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain2y8e Chain A Residue 1177 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2y8e Structure of the Drosophila Melanogaster Rab6 Gtpase at 1.4 A Resolution
Resolution1.39 Å
Binding residue
(original residue number in PDB)		T26 T44
Binding residue
(residue number reindexed from 1)		T17 T35
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) Q71
Catalytic site (residue number reindexed from 1) Q62
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding

View graph for
Molecular Function
External links
PDB RCSB:2y8e, PDBe:2y8e, PDBj:2y8e
PDBsum2y8e
PubMed21795785
UniProtO18334|RAB6_DROME Ras-related protein Rab6 (Gene Name=Rab6)

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