Structure of PDB 2xz7 Chain A Binding Site BS02

Receptor Information

>2xz7 Chain A (length=324) Species: 119072 (Caldanaerobacter subterraneus subsp. tengcongensis)

HMEGLKQLKDLPAETPDGKKVMLAANIGTPKDVASALANGAEGVGLFRTE
FLYMDRNSLPSEEEQFEAYKEVVEKMGGRPVTIRTLDIGGDKELPYLDMP
KEMNPFLGYRAIRLCLDRPDIFKTQLRAILRASAYGNVQIMYPMISSVEE
VRKANSILEEVKAELDREGVKYDKEIKVGIMVEIPSAAVTADILAKEVDF
FSIGTNDLTQYTLAVDRMNEHVKEYYQPFHPAILRLVKMVIDAAHKEGKF
AAMCGEMAGDPLAAVILLGLGLDEFSMSATSIPEIKNIIRNVEYEKAKEI
AEKALNMSEAREIEKMMKDVIKDI

Ligand information

• Ligand ID: MG
• InChI: InChI=1S/Mg/q+2
• InChIKey: JLVVSXFLKOJNIY-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mg+2]
  CACTVS 3.341: [Mg++]
• Formula: Mg
• Name: MAGNESIUM ION
• DrugBank: DB01378
• PDB chain: 2xz7 Chain A Residue 6081

Receptor-Ligand Complex Structure

Structure summary

• PDB: 2xz7 Phosphoenolpyruvate: Sugar Phosphotransferase System from the Hyperthermophilic Thermoanaerobacter Tengcongensis.
• Resolution: 1.83 Å
• Binding residue (original residue number in PDB): E431 D455
• Binding residue (residue number reindexed from 1): E183 D207
• Annotation score: 1

Enzymatic activity

• Catalytic site (original residue number in PDB): E431 S450 D455 C502 E522
• Catalytic site (residue number reindexed from 1): E183 S202 D207 C254 E274
• Enzyme Commision number: 2.7.3.9: phosphoenolpyruvate--protein phosphotransferase.

Gene Ontology

Molecular Function

• GO:0003824 catalytic activity
• GO:0016772 transferase activity, transferring phosphorus-containing groups

Biological Process

• GO:0016310 phosphorylation

External links

• PDB: RCSB:2xz7, PDBe:2xz7, PDBj:2xz7
• PDBsum: 2xz7
• PubMed: 21250658
• UniProt: Q8R7R4