Structure of PDB 2xxa Chain A Binding Site BS02

Receptor Information
>2xxa Chain A (length=413) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NLTDRLSRTLRNISGRGRLTEDNVKDTLREVRMALLEADVALPVVREFIN
RVKEKAVGHEVNKSLTPGQEFVKIVRNELVAAMGEENQTLNLAAQPPAVV
LMAGLQGAGKTTSVGKLGKFLREKHKKKVLVVSADVYRPAAIKQLETLAE
QVGVDFFPSDVGQKPVDIVNAALKEAKLKFYDVLLVDTAGRLHVDEAMMD
EIKQVHASINPVETLFVVDAMTGQDAANTAKAFNEALPLTGVVLTKVDGD
ARGGAALSIRHITGKPIKFLGVGEKTEALEPFHPDRIASRILGMGDVLSL
IEDIESKVDRAQAEKLASKLKKGDGFDLNDFLEQLRQMKNMGGMASLMGK
DDKVLVRMEAIINSMTMKERAKPEIIKGSRKRRIAAGSGMQVQDVNRLLK
QFDDMQRMMKKMK
Ligand information
>2xxa Chain G (length=102) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcauugcuggugcagcgcagcgcggacgcccgaaccuggucagagccgga
aggcagcagccauaagggaugcuuugcgggugccguugccuuccggcaau
gc
<<<<<<<<<<.<<<<<<<<.<<<<<<<<<<<.....<<<<..<.<<<...
.>>>..>.>>>>...>>>.>>.>>>>>>..>>.>>>>>>...>>>>>>>>
>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2xxa The Crystal Structure of the Signal Recognition Particle in Complex with its Receptor.
Resolution3.94 Å
Binding residue
(original residue number in PDB)		K278 A378 N381 S382 M383 T384 M385 S397 R398 R401 G405 S406 G407
Binding residue
(residue number reindexed from 1)		K275 A360 N363 S364 M365 T366 M367 S379 R380 R383 G387 S388 G389
Enzymatic activity
Enzyme Commision number 3.6.5.4: signal-recognition-particle GTPase.
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0008312 7S RNA binding
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0006612 protein targeting to membrane
GO:0006614 SRP-dependent cotranslational protein targeting to membrane
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0048500 signal recognition particle
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2xxa, PDBe:2xxa, PDBj:2xxa
PDBsum2xxa
PubMed21330537
UniProtP0AGD7|SRP54_ECOLI Signal recognition particle protein (Gene Name=ffh)

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