Structure of PDB 2xs7 Chain A Binding Site BS02

Receptor Information
>2xs7 Chain A (length=86) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LPEGKIMPNTVFVGGIDVRMDETEIRSFFARYGSVKEVKIITDRTGVSKG
YGFVSFYNDVDVQKIVESQINFHGKKLKLGPAIRKQ
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain2xs7 Chain A Residue 1118 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2xs7 Kinked Beta-Strands Mediate High-Affinity Recognition of Mrna Targets by the Germ-Cell Regulator Dazl
Resolution1.45 Å
Binding residue
(original residue number in PDB)
E55 H104
Binding residue
(residue number reindexed from 1)
E24 H73
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0003730 mRNA 3'-UTR binding

View graph for
Molecular Function
External links
PDB RCSB:2xs7, PDBe:2xs7, PDBj:2xs7
PDBsum2xs7
PubMed22021443
UniProtQ64368|DAZL_MOUSE Deleted in azoospermia-like (Gene Name=Dazl)

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