Structure of PDB 2xrz Chain A Binding Site BS02

Receptor Information
>2xrz Chain A (length=450) Species: 192952 (Methanosarcina mazei Go1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HMNPKRIRALKSGKQGDGPVVYWMSRDQRAEDNWALLFSRAIAKEANVPV
VVVFCLTDEFLEAGIRQYEFMLKGLQELEVSLSRKKIPSFFLRGDPGEKI
SRFVKDYNAGTLVTDFSPLRIKNQWIEKVISGISIPFFEVDAHNVVPCWE
ASQKHEYAAHTFRPKLYALLPEFLEEFPELEPNSVETLSDVLETGVKALL
PERALLKNKDPLFEPWHFEPGEKAAKKVMESFIADRLDSYGALRNDPTKN
MLSNLSPYLHFGQISSQRVVLEVEKAESNPGSKKAFLDEILIWKEISDNF
CYYNPGYDGFESFPSWAKESLNAHRNDVRSHIYTLEEFEAGKTHDPLWNA
SQMELLSTGKMHGYTRMYWAKKILEWSESPEKALEIAICLNDRYELDGRD
PNGYAGIAWSIGGVHDRAWGEREVTGKIRYMSYEGCKRKFDVKLYIEKYS
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2xrz Crystal Structures of an Archaeal Class II DNA Photolyase and its Complex with Uv-Damaged Duplex DNA.
Resolution2.2 Å
Binding residue
(original residue number in PDB)		Y158 R429 A430 W431
Binding residue
(residue number reindexed from 1)		Y157 R417 A418 W419
Binding affinityPDBbind-CN: Kd=44nM
Enzymatic activity
Catalytic site (original residue number in PDB) E301 W305 A335 G375
Catalytic site (residue number reindexed from 1) E289 W293 A323 G363
Enzyme Commision number 4.1.99.3: deoxyribodipyrimidine photo-lyase.
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003677 DNA binding
GO:0003904 deoxyribodipyrimidine photo-lyase activity
GO:0016829 lyase activity
Biological Process
GO:0000719 photoreactive repair
GO:0006281 DNA repair

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Molecular Function
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Biological Process
External links
PDB RCSB:2xrz, PDBe:2xrz, PDBj:2xrz
PDBsum2xrz
PubMed21892138
UniProtQ8PYK9

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