Structure of PDB 2xgp Chain A Binding Site BS02

Receptor Information
>2xgp Chain A (length=510) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RMSKFTWKELIQLGSPSKAYESSLACIAHIDMNAFFAQVEQMRCGLSKED
PVVCVQWNSIIAVSYAARKYGISRMDTIQEALKKCSNLIPIHTAVFKKGE
DFWQYHDGCGSWVQDPAKQISVEDHKVSLEPYRRESRKALKIFKSACDLV
ERASIDEVFLDLGRICFNMLMFDNEYELTGDLKLKDALSNIREAFIGGNY
DINSHLPLIPEKIKSLKFEGDVFNPEGRDLITDWDDVILALGSQVCKGIR
DSIKDILGYTTSCGLSSTKNVCKLASNYKKPDAQTIVKNDCLLDFLDCGK
FEITSFWTLGGVLGKELIDVLDLPHENSIKHIRETWPDNAGQLKEFLDAK
VKQSDYDRSTSNIDPLKTADLAEKLFKLSRGRYGLPLSSRPVVKSMMSNK
NLRGKSCNSIVDCISWLEVFCAELTSRIQDLEQEYNKIVIPRTVSISLKT
KSYEVYRKSGPVAYKGINFQSHELLKVGIKFVTDLDIKGKNKSYYPLTKL
SMTITNFDII
Ligand information
Receptor-Ligand Complex Structure
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PDB2xgp Mechanism of Replication Blocking and Bypass of Y-Family Polymerase Eta by Bulky Acetylaminofluorene DNA Adducts.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		Q55 I60 K125 S358 V392 K393 S394 M395 M396 N398 R426
Binding residue
(residue number reindexed from 1)		Q56 I61 K126 S359 V393 K394 S395 M396 M397 N399 R427
Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Gene Ontology
Molecular Function
GO:0003684 damaged DNA binding
Biological Process
GO:0006281 DNA repair

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Molecular Function
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Biological Process
External links
PDB RCSB:2xgp, PDBe:2xgp, PDBj:2xgp
PDBsum2xgp
PubMed21076032
UniProtQ04049|POLH_YEAST DNA polymerase eta (Gene Name=RAD30)

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