Structure of PDB 2wwb Chain A Binding Site BS02

Receptor Information
>2wwb Chain A (length=476) Species: 9615 (Canis lupus familiaris) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MAIKFLEVIKPFCVILPEIQKPERKIQFKEKVLWTAITLFIFLVCCQIPL
FGIMSSDSADPFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKII
EVGDTPKDRALFNGAQKLFGMIITIGQSIVYVMTGMYGDPSEMGAGICLL
ITIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPTT
VNTGRGMEFEGAIIALFHLLATRTDKVRALREAFYRQNLPNLMNLIATIF
VFAVVIYFQGFRVDLPIKSARYRGQYNTYPIKLFYTSNIPIILQSALVSN
LYVISQMLSARFSGNLLVSLLGTWSDTSSGGPARAYPVGGLCHYLSPPES
FGSVLEDPVHAVVYIVFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMV
MRGHRETSMVHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLA
VTIIYQYFEIFVKEQSEVGSMGALLF
Ligand information
>2wwb Chain F (length=25) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ccacgucaacagcaguuggacgugg
<<<<<<...<<.....>>.>>>>>>
Receptor-Ligand Complex Structure
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PDB2wwb Structure of Monomeric Yeast and Mammalian Sec61 Complexes Interacting with the Translating Ribosome.
Resolution6.48 Å
Binding residue
(original residue number in PDB)		R271 R273 R402 G403 H404 R405 E406
Binding residue
(residue number reindexed from 1)		R271 R273 R402 G403 H404 R405 E406
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005048 signal sequence binding
GO:0005515 protein binding
GO:0008320 protein transmembrane transporter activity
GO:0043022 ribosome binding
Biological Process
GO:0006613 cotranslational protein targeting to membrane
GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation
GO:0015031 protein transport
GO:0031204 post-translational protein targeting to membrane, translocation
GO:0039019 pronephric nephron development
GO:0045047 protein targeting to ER
GO:0045048 protein insertion into ER membrane
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005784 Sec61 translocon complex
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2wwb, PDBe:2wwb, PDBj:2wwb
PDBsum2wwb
PubMed19933108
UniProtP38377|S61A1_CANLF Protein transport protein Sec61 subunit alpha isoform 1 (Gene Name=SEC61A1)

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