Structure of PDB 2ww9 Chain A Binding Site BS02

Receptor Information
>2ww9 Chain A (length=490) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MSGFRLIDIVKPILPILPEVELPFEKLPFDDKIVYTIFAGLIYLFAQFPL
VGLPKATTPNVNDPIYFLRGVFGCEPRTLLEFGLFPNISSGLILQLLAGL
KVIKVNFKIQSDRELFQSLTKVFAIVQYVILTNIFIFAGYFGDDLSVVQI
GLINFQLVGAGIFTTLLAEVIDKGFGFSSGAMIINTVVIATNLVADTFGV
SQIKVGEDDQTEAQGALINLIQGLRSKHKTFIGGIISAFNRDYLPNLTTT
IIVLAIAIIVCYLQSVRVELPIRSTRARGTNNVYPIKLLYTGCLSVLFSY
TILFYIHIFAFVLIQLVAKNEPTHIICKIMGHYENANNLLAVPTFPLSLL
APPTSFFKGVTQQPLTFITYSAFILVTGIWFADKWQAISGSSARDVALEF
KDQGITLMGRREQNVAKELNKVIPIAAVTGASVLSLITVIGESLGLKGKA
AGIVVGIAGGFSLLEVITIEYQQSGGQSALNQVLGVPGAM
Ligand information
>2ww9 Chain D (length=63) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
agaacgcagcgaaaugcgauacguaaugugaauugcagaauuccgugaau
caucgaaucuuug
.<<<<<<........>>>.....<.<<....<<<....>>>.........
.>>..>...>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB2ww9 Structure of Monomeric Yeast and Mammalian Sec61 Complexes Interacting with the Translating Ribosome.
Resolution8.6 Å
Binding residue
(original residue number in PDB)		R273 S274 R276 A277 R278 G279 R410 E412 Q413 N414 E418
Binding residue
(residue number reindexed from 1)		R273 S274 R276 A277 R278 G279 R410 E412 Q413 N414 E418
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005048 signal sequence binding
GO:0005515 protein binding
GO:0008320 protein transmembrane transporter activity
GO:0043022 ribosome binding
Biological Process
GO:0006614 SRP-dependent cotranslational protein targeting to membrane
GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation
GO:0015031 protein transport
GO:0031204 post-translational protein targeting to membrane, translocation
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005784 Sec61 translocon complex
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
GO:0071261 Ssh1 translocon complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:2ww9, PDBe:2ww9, PDBj:2ww9
PDBsum2ww9
PubMed19933108
UniProtP38353|SSH1_YEAST Sec sixty-one protein homolog (Gene Name=SSH1)

[Back to BioLiP]