Structure of PDB 2wul Chain A Binding Site BS02

Receptor Information
>2wul Chain A (length=109) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SAEQLDALVKKDKVVVFLKGTPEQPQCGFSNAVVQILRLHGVRDYAAYNV
LDDPELRQGIKDYSNWPTIPQVYLNGEFVGGCDILLQMHQNGDLVEELKK
LGIHSALLD
Ligand information
Ligand IDFES
InChIInChI=1S/2Fe.2S
InChIKeyNIXDOXVAJZFRNF-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04[Fe]1S[Fe]S1
CACTVS 3.341
OpenEye OEToolkits 1.5.0		S1[Fe]S[Fe]1
FormulaFe2 S2
NameFE2/S2 (INORGANIC) CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain2wul Chain A Residue 1150 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2wul The Crystal Structure of Human Glrx5: Iron Sulphur Cluster Coordination, Tetrameric Assembly and Monomer Activity.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		K59 C67 F69
Binding residue
(residue number reindexed from 1)		K19 C27 F29
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0015036 disulfide oxidoreductase activity

View graph for
Molecular Function
External links
PDB RCSB:2wul, PDBe:2wul, PDBj:2wul
PDBsum2wul
PubMed21029046
UniProtQ86SX6|GLRX5_HUMAN Glutaredoxin-related protein 5, mitochondrial (Gene Name=GLRX5)

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