Structure of PDB 2w72 Chain A Binding Site BS02
Receptor Information
>2w72 Chain A (length=141) Species:
9606
(Homo sapiens) [
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VLSPADKTNVKAAWGKVGAHAGEYGAEAYERMFLSFPTTKTYFPHFDLSH
GSAQVKGQGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKL
LSHCLLVTLAAHLPAEFTPAVHASLDKFLASVSTVLTSKYR
Ligand information
Ligand ID
XE
InChI
InChI=1S/Xe
InChIKey
FHNFHKCVQCLJFQ-UHFFFAOYSA-N
SMILES
Software
SMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0
[Xe]
Formula
Xe
Name
XENON
ChEMBL
CHEMBL1236802
DrugBank
DB13453
ZINC
PDB chain
2w72 Chain A Residue 1146 [
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Receptor-Ligand Complex Structure
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PDB
2w72
Pattern of Cavities in Globins: The Case of Human Hemoglobin.
Resolution
1.07 Å
Binding residue
(original residue number in PDB)
W14 F128
Binding residue
(residue number reindexed from 1)
W14 F128
Annotation score
1
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0004601
peroxidase activity
GO:0005344
oxygen carrier activity
GO:0005506
iron ion binding
GO:0005515
protein binding
GO:0019825
oxygen binding
GO:0020037
heme binding
GO:0031720
haptoglobin binding
GO:0043177
organic acid binding
GO:0046872
metal ion binding
Biological Process
GO:0015670
carbon dioxide transport
GO:0015671
oxygen transport
GO:0030185
nitric oxide transport
GO:0042542
response to hydrogen peroxide
GO:0042744
hydrogen peroxide catabolic process
GO:0098869
cellular oxidant detoxification
Cellular Component
GO:0005576
extracellular region
GO:0005615
extracellular space
GO:0005829
cytosol
GO:0005833
hemoglobin complex
GO:0016020
membrane
GO:0031838
haptoglobin-hemoglobin complex
GO:0070062
extracellular exosome
GO:0071682
endocytic vesicle lumen
GO:0072562
blood microparticle
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Molecular Function
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Biological Process
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Cellular Component
External links
PDB
RCSB:2w72
,
PDBe:2w72
,
PDBj:2w72
PDBsum
2w72
PubMed
19365817
UniProt
P69905
|HBA_HUMAN Hemoglobin subunit alpha (Gene Name=HBA1)
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