Structure of PDB 2vwd Chain A Binding Site BS02

Receptor Information
>2vwd Chain A (length=413) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NICLQKTSNQILKPKLISTLPVVGQSGTCITDPLLAMDEGYFAYSHLERI
GSCGVSKQRIIGVGEVLDRGDEVPSLFMTNVWTPPNPNTVYHCSAVYNNE
FYYVLCAVSTVGDPILNSTYWSGSLMMTRLAVKPKSNGGGYNQHQLALRS
IEKGRYDKVMPYGPSGIKQGDTLYFPAVGFLVRTEFKYNDSNCPITKCQY
SKPENCRLSMGIRPNSHYILRSGLLKYNLSDGENPKVVFIEISDQRLSIG
SPSKIYDSLGQPVFYQASFSWDTMIKFGDVLTVNPLVVNWRNNTVISRPG
QSQCPRFNTCPEICWEGVYNDAFLIDRINWISAGVFLDSNQTAENPVFTV
FKDNEILYRAQLASEDTNAQKTITNCFLLKNKIWCISLVEIYDTGDNVIR
PKLFAVKIPEQCT
Ligand information
Ligand IDGBL
InChIInChI=1S/C4H6O2/c5-4-2-1-3-6-4/h1-3H2
InChIKeyYEJRWHAVMIAJKC-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C1CC(=O)OC1
ACDLabs 10.04O=C1OCCC1
CACTVS 3.341O=C1CCCO1
FormulaC4 H6 O2
NameGAMMA-BUTYROLACTONE;
DIHYDROFURAN-2(3H)-ONE
ChEMBLCHEMBL95681
DrugBankDB04699
ZINCZINC000004658567
PDB chain2vwd Chain A Residue 1604 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2vwd Crystal Structure and Carbohydrate Analysis of Nipah Virus Attachment Glycoprotein: A Template for Antiviral and Vaccine Design.
Resolution2.25 Å
Binding residue
(original residue number in PDB)		P323 K324 S325
Binding residue
(residue number reindexed from 1)		P134 K135 S136
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0046789 host cell surface receptor binding
Biological Process
GO:0019058 viral life cycle
Cellular Component
GO:0019031 viral envelope

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2vwd, PDBe:2vwd, PDBj:2vwd
PDBsum2vwd
PubMed18815311
UniProtQ9IH62|GLYCP_NIPAV Glycoprotein G (Gene Name=G)

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