Structure of PDB 2v6e Chain A Binding Site BS02

Receptor Information

>2v6e Chain A (length=531) Species: 255431 (Klebsiella phage phiKO2) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

VKIGELINSLVSEVEAIDASDRPQGDKTKKIKAAALKYKNALFNDKRKFR
GKGLEKRISANTFNSYMSRARKRFDDRLHHNFEKNVIKLSEKYPLYSEEL
SSWLSMPAASIRQHMSRLQAKLKEIMPLAEDLSNIKIGTKNSEAKINKLA
NKYPEWQFAISDLNSEDWKDKRDYLYKLFQQGSSLLEDLNNLKVNHEVLY
HLQLSSAERTSIQQRWANVLSEKKRNVVVIDYPRYMQAIYDIINKPIVSF
DLTTRRGMAPLAFALAALSGRRMIEIMLQGEFSVAGKYTVTFLGQAKKRS
EDKGISRKIYTLCDATLFVSLVNELRSCPAAADFDEVIKGYGENDTRSEN
GRINAILATAFNPWVKTFLGDDRRVYKDSRAIYARIAYEMFFRVDPRWKN
VDEDVFFMEILGHDDENTQLHYKQFKLANFSRTWRPNVGEENARLAALQK
LDSMMPDFARGDAGVRIHETVKQLVEQDPSIKITNSTLRPFNFSTRLIPR
YLEFAADALGQFVGENGQWQLKDEAPAIVLP

Ligand information

>2v6e Chain D (length=19) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

cacacaattgcccattata

Receptor-Ligand Complex Structure

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Structure summary

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PDB	2v6e An Interlocked Dimer of the Protelomerase Telk Distorts DNA Structure for the Formation of Hairpin Telomeres
Resolution	3.2 Å
Binding residue (original residue number in PDB)	G7 E8 L9 I61 S62 N64 T65 Y69 W219 K226 T257 R258 R259 K300 Y344 R350 A358 T362 K380 H424 Y425
Binding residue (residue number reindexed from 1)	G4 E5 L6 I58 S59 N61 T62 Y66 W216 K223 T254 R255 R256 K297 Y341 R347 A355 T359 K377 H421 Y422
Binding affinity	PDBbind-CN: Kd=17nM

Enzymatic activity

Enzyme Commision number

3.1.22.-

External links

PDB	RCSB:2v6e, PDBe:2v6e, PDBj:2v6e
PDBsum	2v6e
PubMed	17889664
UniProt	Q6UAV6\|PTELO_BPKO2 Protelomerase (Gene Name=26)

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