Structure of PDB 2v4j Chain A Binding Site BS02

Receptor Information
>2v4j Chain A (length=436) Species: 882 (Nitratidesulfovibrio vulgaris str. Hildenborough) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AKHATPKLDQLESGPWPSFVSDIKQEAAYRAANPKGLDYQVPVDCPEDLL
GVLELSYDEGETHWKHGGIVGVFGYGGGVIGRYCDQPEKFPGVAHFHTVR
VAQPSGKYYSADYLRQLCDIWDLRGSGLTNMHGSTGDIVLLGTQTPQLEE
IFFELTHNLNTDLGGSGSNLRTPESCLGKSRCEFACYDSQAACYELTMEY
QDELHRPAFPYKFKFKFDACPNGCVASIARSDFSVIGTWKDDIKIDAEAV
KAYVAGEFKPNAGAHSGRDWGKFDIEAEVVNRCPSKCMKWDGSKLSIDNK
ECVRCMHCINTMPRALHIGDERGASILCGAKAPILDGAQMGSLLVPFVAA
EEPFDEIKEVVEKIWDWWMEEGKNRERLGETMKRLSFQKLLEVTEIAPVP
QHVKEPRTNPYIFFKEEEVPGGWDRDITEYRKRHLR
Ligand information
Ligand IDSF4
InChIInChI=1S/4Fe.4S
InChIKeyLJBDFODJNLIPKO-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.7[S]12[Fe]3[S]4[Fe]1[S]5[Fe]2[S]3[Fe]45
CACTVS 3.385S1[Fe]S[Fe]1.S2[Fe]S[Fe]2
FormulaFe4 S4
NameIRON/SULFUR CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain2v4j Chain A Residue 502 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB2v4j The Crystal Structure of Desulfovibrio Vulgaris Dissimilatory Sulfite Reductase Bound to Dsrc Provides Novel Insights Into the Mechanism of Sulfate Respiration.
Resolution2.1 Å
Binding residue
(original residue number in PDB)		C284 P285 C288 M289 C303 V304 R305 C306 M307 C309
Binding residue
(residue number reindexed from 1)		C283 P284 C287 M288 C302 V303 R304 C305 M306 C308
Annotation score3
Enzymatic activity
Enzyme Commision number 1.8.99.3: Transferred entry: 1.8.99.5.
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0016002 sulfite reductase activity
GO:0016491 oxidoreductase activity
GO:0018551 dissimilatory sulfite reductase activity
GO:0020037 heme binding
GO:0046872 metal ion binding
GO:0050311 sulfite reductase (ferredoxin) activity
GO:0051536 iron-sulfur cluster binding
GO:0051539 4 iron, 4 sulfur cluster binding
Biological Process
GO:0000103 sulfate assimilation
Cellular Component
GO:0009337 sulfite reductase complex (NADPH)

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:2v4j, PDBe:2v4j, PDBj:2v4j
PDBsum2v4j
PubMed18829451
UniProtP45574|DSVA_NITV2 Sulfite reductase, dissimilatory-type subunit alpha (Gene Name=dsvA)

[Back to BioLiP]