Structure of PDB 2uwn Chain A Binding Site BS02

Receptor Information
>2uwn Chain A (length=187) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MGLKPCDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYW
DHIHCTQDGWSPAVPCLRKCYFPYLENGYNQNHGRKFVQGKSIDVACHPG
YALPKAQTTVTCMENGWSPTPRCIRVKTCSKSSIDIENGFISESQYTYAL
KEKAKYQCKLGYVTADGETSGSITCGKDGWSAQPTCI
Ligand information
Ligand IDSO4
InChIInChI=1S/H2O4S/c1-5(2,3)4/h(H2,1,2,3,4)/p-2
InChIKeyQAOWNCQODCNURD-UHFFFAOYSA-L
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0[O-]S(=O)(=O)[O-]
CACTVS 3.341[O-][S]([O-])(=O)=O
ACDLabs 10.04[O-]S([O-])(=O)=O
FormulaO4 S
NameSULFATE ION
ChEMBL
DrugBankDB14546
ZINC
PDB chain2uwn Chain A Residue 1513 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2uwn Structural Basis for Complement Factor H Linked Age-Related Macular Degeneration.
Resolution2.35 Å
Binding residue
(original residue number in PDB)		V407 K410
Binding residue
(residue number reindexed from 1)		V88 K91
Annotation score3
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:2uwn, PDBe:2uwn, PDBj:2uwn
PDBsum2uwn
PubMed17893204
UniProtP08603|CFAH_HUMAN Complement factor H (Gene Name=CFH)

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