Structure of PDB 2rje Chain A Binding Site BS02

Receptor Information

>2rje Chain A (length=309) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

WSWESYLEEQKAITAPVSLFQDSQAVTHNKNGFKLGMKLEGIDPQHPSMY
FILTVAEVCGYRLRLHFDGYSECHDFWVNANSPDIHPAGWFEKTGHKLQP
PKGYFSWSQYLRSTRAQAAPKHLFVSQSHSPPPLGFQVGMKLEAVDRMNP
SLVCVASVTDVVDSRFLVHFDNWDDTYDYWCDPSSPYIHPVGWCQKQGKP
LTPPQDYPDPDNFCWEKYLEETGASAVPTWAFKVRPPHSFLVNMKLEAVD
RRNPALIRVASVEDVEDHRIKIHFDGWSHGYDFWIDADHPDIHPAGWCSK
TGHPLQPPL

Ligand information

>2rje Chain Q (length=8) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

HRKVLRDN

Receptor-Ligand Complex Structure

Global view

Local view

Structure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

PDB	2rje L3MBTL1 recognition of mono- and dimethylated histones.
Resolution	1.86 Å
Binding residue (original residue number in PDB)	W382 Y386
Binding residue (residue number reindexed from 1)	W173 Y177

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Biological Process
GO:0006355	regulation of DNA-templated transcription

	Cellular Component
GO:0005634	nucleus

View graph for
Biological Process

View graph for
Cellular Component

External links

PDB	RCSB:2rje, PDBe:2rje, PDBj:2rje
PDBsum	2rje
PubMed	18026117
UniProt	Q9Y468\|LMBL1_HUMAN Lethal(3)malignant brain tumor-like protein 1 (Gene Name=L3MBTL1)

[Back to BioLiP]