Structure of PDB 2rdl Chain A Binding Site BS02

Receptor Information
>2rdl Chain A (length=226) Species: 10036 (Mesocricetus auratus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IIGGTECRPHARPYMAYLEIVTPENHLSACSGFLIRRNFVMTAAHCAGRS
ITVLLGAHNKKVKEDTWQKLEVEKQFPHPKYDDRLVLNDIMLLKLKEKAN
LTLGVGTLPISAKSNSIPPGRVCRAVGWGRTNVNEPPSDTLQEVKMRILD
PQACKHFEDFHQEPQLCVGNPKKIRNVYKGDSGGPLLCAGIAQGIASYVL
RNAKPPSVFTRISHYRPWINKILREN
Ligand information
Receptor-Ligand Complex Structure
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PDB2rdl Structural basis for elastolytic substrate specificity in rodent alpha-chymases.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		H57 S195
Binding residue
(residue number reindexed from 1)		H45 S182
Enzymatic activity
Catalytic site (original residue number in PDB) H57 D102 G193 S195 G196
Catalytic site (residue number reindexed from 1) H45 D89 G180 S182 G183
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
GO:0008236 serine-type peptidase activity
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0043231 intracellular membrane-bounded organelle

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2rdl, PDBe:2rdl, PDBj:2rdl
PDBsum2rdl
PubMed17981788
UniProtO70164

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