Structure of PDB 2ram Chain A Binding Site BS02

Receptor Information
>2ram Chain A (length=273) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPTIKINGYTG
PGTVRISLVTKDPPHRPHPHELVGKDCRDGYYEADLCPDRSIHSFQNLGI
QCVKKRDLEQAISQRIQTNNNPFHVPIEEQRGDYDLNAVRLCFQVTVRDP
AGRPLLLTPVLSHPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDK
VQKEDIEVYFTGPGWEARGSFSQADVHRQVAIVFRTPPYADPSLQAPVRV
SMQLRRPSDRELSEPMEFQYLPD
Ligand information
Receptor-Ligand Complex Structure
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PDB2ram A novel DNA recognition mode by the NF-kappa B p65 homodimer.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		R33 R35 S42 G44
Binding residue
(residue number reindexed from 1)		R15 R17 S24 G26
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2ram, PDBe:2ram, PDBj:2ram
PDBsum2ram
PubMed9437432
UniProtQ04207|TF65_MOUSE Transcription factor p65 (Gene Name=Rela)

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