Structure of PDB 2qic Chain A Binding Site BS02

Receptor Information
>2qic Chain A (length=51) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EPTYCLCNQVSYGEMIGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCRG
E
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain2qic Chain A Residue 300 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2qic Histone H3K4me3 binding is required for the DNA repair and apoptotic activities of ING1 tumor suppressor.
Resolution2.1 Å
Binding residue
(original residue number in PDB)		C213 C215 H237 C240
Binding residue
(residue number reindexed from 1)		C5 C7 H29 C32
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:2qic, PDBe:2qic, PDBj:2qic
PDBsum2qic
PubMed18533182
UniProtQ9UK53|ING1_HUMAN Inhibitor of growth protein 1 (Gene Name=ING1)

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