Structure of PDB 2pok Chain A Binding Site BS02

Receptor Information
>2pok Chain A (length=458) Species: 170187 (Streptococcus pneumoniae TIGR4) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AMVFPSEQEQIEKFEKDHVAQHYFEVLRTLISKKSVFAQQVGLKEVANYL
GEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGD
QVWTEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNI
SFIMEGAEESASTDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGG
NKGIVTFDAKVKSADVDIHSSYGGVVESAPWYLLQALQSLRAADGRILVE
GLYEEVQEPNEREMALLETYGQRNPEEVSRIYGLELPLLQEERMAFLKRF
FFDPALNIEGIQSGYQGQGVKTILPAEASAKLEVRLVPGLEPHDVLEKIR
KQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYPQGVSVLP
TTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELV
EELIRSYE
Ligand information
Ligand IDBGC
InChIInChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6-/m1/s1
InChIKeyWQZGKKKJIJFFOK-VFUOTHLCSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.7.6C(C1C(C(C(C(O1)O)O)O)O)O
CACTVS 3.370OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O
CACTVS 3.370OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
OpenEye OEToolkits 1.7.6C([C@@H]1[C@H]([C@@H]([C@H]([C@@H](O1)O)O)O)O)O
ACDLabs 12.01OC1C(O)C(OC(O)C1O)CO
FormulaC6 H12 O6
Namebeta-D-glucopyranose;
beta-D-glucose;
D-glucose;
glucose
ChEMBLCHEMBL1614854
DrugBankDB02379
ZINCZINC000003833800
PDB chain2pok Chain A Residue 459 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2pok Crystal structure of a M20 family metallo peptidase from Streptococcus pneumoniae.
Resolution1.9 Å
Binding residue
(original residue number in PDB)		Q256 N259 E262 R372 S373 D374
Binding residue
(residue number reindexed from 1)		Q257 N260 E263 R373 S374 D375
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0009014 succinyl-diaminopimelate desuccinylase activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0009089 lysine biosynthetic process via diaminopimelate
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2pok, PDBe:2pok, PDBj:2pok
PDBsum2pok
PubMed
UniProtA0A0H2UN21

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