Structure of PDB 2pnx Chain A Binding Site BS02

Receptor Information
>2pnx Chain A (length=51) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCPRCSQ
E
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain2pnx Chain A Residue 300 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2pnx ING4 mediates crosstalk between histone H3 K4 trimethylation and H3 acetylation to attenuate cellular transformation
Resolution1.8 Å
Binding residue
(original residue number in PDB)		C199 C201 H223 C226
Binding residue
(residue number reindexed from 1)		C5 C7 H29 C32
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:2pnx, PDBe:2pnx, PDBj:2pnx
PDBsum2pnx
PubMed19187765
UniProtQ9UNL4|ING4_HUMAN Inhibitor of growth protein 4 (Gene Name=ING4)

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