Structure of PDB 2oh2 Chain A Binding Site BS02

Receptor Information
>2oh2 Chain A (length=428) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KEKINKIIMEATKGSRFYGNELKKEKQVNQRIENMMQQKAQITSQQLRKA
QLQVDRFAMELEQSRNLSNTIVHIDMDAFYAAVEMRDNPELKDKPIAVGS
MSMLSTSNYHARRFGVRAAMPGFIAKRLCPQLIIVPPNFDKYRAVSKEVK
EILADYDPNFMAMSLDEAYLNITKHLEERQNWPEDKRRYFIKNSVVFGTS
AQEVVKEIRFRIEQKTTLTASAGIAPNTMLAKVCSDKNKPNGQYQILPNR
QAVMDFIKDLPIRKVSGIGKVTEKMLKALGIITCTELYQQRALLSLLFSE
TSWHYFLHISLGLGSTHLTRDGERKSMSVERTFSEINKAEEQYSLCQELC
SELAQDLQKERLKGRTVTIKLKNVNFEVKTRASTVSSVVSTAEEIFAIAK
ELLKTEIDADFPHPLRLRLMGVRISSFP
Ligand information
Receptor-Ligand Complex Structure
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PDB2oh2 Ternary complex of the catalytic core of human DNA polymerase Kappa with DNA and dTT
Resolution3.05 Å
Binding residue
(original residue number in PDB)		T44 F49 M135 P153 S388 T390 R413 K414 S415 M416 V418 E419 R420 T421 R507
Binding residue
(residue number reindexed from 1)		T12 F17 M103 P121 S299 T301 R324 K325 S326 M327 V329 E330 R331 T332 R418
Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Gene Ontology
Molecular Function
GO:0003684 damaged DNA binding
GO:0003887 DNA-directed DNA polymerase activity
Biological Process
GO:0006281 DNA repair

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Molecular Function
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Biological Process
External links
PDB RCSB:2oh2, PDBe:2oh2, PDBj:2oh2
PDBsum2oh2
PubMed
UniProtQ9UBT6|POLK_HUMAN DNA polymerase kappa (Gene Name=POLK)

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